PCI
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FAME Trial: FFR-Guided PCI Versus Angiography-Guided PCI in Multivessel CAD
The FAME trial was a landmark cardiology trial that changed how interventional cardiologists think about coronary stenoses in patients with multivessel coronary artery disease. Instead of relying only on angiographic appearance, the FAME trial tested whether using fractional flow reserve, or FFR, to guide PCI could improve outcomes compared with angiography-guided PCI alone. The main…
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COURAGE Trial: Optimal Medical Therapy With or Without PCI for Stable Coronary Disease
The COURAGE trial was one of the most important landmark cardiology trials because it challenged the routine use of percutaneous coronary intervention, or PCI, in patients with stable coronary artery disease. Before COURAGE, many patients with stable coronary blockages underwent PCI with the expectation that opening the artery would reduce future heart attacks or death.…