ACT
2011, Acetylcysteine in Coronary Angiography

---

ATTR-ACT
2018, Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy

---

AATAC
2016, Ablation vs. amiodarone for persistent atrial fibrillation in patients with CHF

---

NOBLE
2016, Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis

---

DOREMI
2021, Milrinone as compared with Dobutamine in the treatment of Cardiogenic shock

---

CREST
2010, Stenting versus CEA in Carotid-Artery Stenosis

---

ADAPTABLE
2021, High vs. Low Dose Aspirin in Cardiovascular Disease

---

A-HeFT
2004, Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure

---

ACCOMPLISH
2008, Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients

---

EXPLORER-HCM
2020, Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy

---

DANISH
2016, Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure

---

AIM HIGH
2011, Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

---

AIMS
2019, Irbesartan in Marfan syndrome

---

COVERT MI
2021, Effect of colchicine on myocardial injury in acute myocardial infarction

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COMPLETE
2019, Complete Revascularization with Multivessel PCI for Myocardial Infarction

---

AIRTRIP
2016, Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence

---

EUCLID
2017, Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

---

REVERT
2015, Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias

---

CTCR-MVS
2021, Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation

---

ALIVE
2002, Amiodarone as Compared with Lidocaine for Shock-Resistant Ventricular Fibrillation

---

VANISH
2016, Ventricular Tachycardia Ablation versus Escalation of Antiarrhythmic Drugs

---

Colchicine cream in AK Trial
2018, 0·5% colchicine cream vs. photodynamic therapy in actinic keratosis

---

COMBI-V
2015, Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib

---

HALT-IT
2020, Effects of Tranexamic acid (TXA) on death and thromboembolic events in patients with acute GI bleeds

---

ALIVE
2002, Amiodarone as Compared with Lidocaine for Shock-Resistant Ventricular Fibrillation

---

RAPID-TnT
2019, Rapid Assessment of Possible ACS in the Emergency Department With High-Sensitivity Troponin T

---

CRASH-2
2010, Effects of tranexamic acid in trauma patients with significant haemorrhage

---

ACCORD
2008, Effects of Intensive Glucose Lowering in Type 2 Diabetes

---

Teprotumumab for Thyroid-Associated Ophthalmopathy
2017, Teprotumumab for Thyroid-Associated Ophthalmopathy

---

TABLET
2019, Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception

---

ATTIRE
2021, Albumin Infusions in Hospitalized Patients with Cirrhosis

---

CRCPilotNorway
2020, Colorectal Cancer Screening With Repeated Fecal Immunochemical Test Versus Sigmoidoscopy

---

COGENT
2010, Clopidogrel with or without Omeprazole in Coronary Artery Disease

---

Timing of Endoscopy in UGIB
2020, Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding

---

FMT in UC
2019, Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis

---

DHOPE-DCD
2021, Hypothermic Machine Perfusion in Liver Transplantation

---

DIETFITS
2020, Low-fat vs low-carbohydrate diet on weight loss & the association with genotype pattern or insulin secretion

---

CAMELLIA-TIMI 61
2019, Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients

---

PANTER
2010, A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis

---

ENVISION
2020, Phase 3 trial of RNAi therapeutic givosiran for acute intermittent porphyria

---

APOLLO
2018, Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

---

DEXACET
2019, Effect of Acetaminophen on postoperative delirium among older patients following cardiac surgery

---

CHOIR
2006, Erythropoetin for anemia in non-dialysis CKD

---

AGE
2006, Mammographic screening from age 40 years

---

COLONPREV
2012, FIT vs. colonoscopy for colon cancer screening

---

FREGAT
2019, Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer

---

REACH2
2020, Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease

---

CLASS-01
2019, Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in locally advanced gastric cancer

---

INO-VATE ALL
2016, Inotuzumab Ozogamicin versus Standard Therapy for Acute Lymphoblastic Leukemia

---

ALEX
2017, Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer

---

POLLUX
2016, Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma

---

COMFORT-I
2012, Ruxolitinib for Myelofibrosis

---

HIPEC in Ovarian Cancer
2018, Hyperthermic intraperitoneal chemotherapy in ovarian cancer

---

CYTO-PV
2013, Cardiovascular Events and Intensity of Treatment in Polycythemia Vera

---

ERSPC
2009, Screening and Prostate-Cancer Mortality

---

CheckMate 214
2018, Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

---

HOPE
2019, A phase 3 randomized trial of voxelotor in sickle cell disease

---

HERCULES
2019, Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

---

ADJUST PE
2014, Age Adjusted D Dimer for PE

---

ACTIV-3
2020, Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

---

ICTOC
2020, Compression Therapy to Prevent Recurrent Cellulitis of the Leg

---

EASE
2012, Early Surgery versus Conventional Treatment for Infective Endocarditis

---

ANRS IPERGAY
2015, On-demand preexposure prophylaxis in men at high risk for HIV-1 infection

---

DAHHS2
2019, Treatment of acute hepatitis C with 8 weeks of grazoprevir plus elbasvir

---

AIDA-WP2
2018, 5-Day nitrofurantoin vs single-dose fosfomycin for uncomplicated UTI in women

---

PLEASE
2016, Longer-Term Therapy for Symptoms Attributed to Lyme Disease

---

OVIVA
2019, Oral versus Intravenous Antibiotics for Bone and Joint Infection

---

ADRENAL
2018, Glucocorticoids in Septic Shock

---

NIX-TB
2020, Treatment of Highly Drug-Resistant Pulmonary Tuberculosis

---

CARRESS HF
2012, Ultrafiltration in Decompensated Heart Failure with Cardiorenal Syndrome

---

AKIKI
2016, Renal Replacement Therapy in ICU

---

SALT
2006, Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia

---

BLISS-LN
2020, Belimumab in Lupus Nephritis
2020, Belimumab in Lupus Nephritis

---

CLICK
2021, Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease

---

ILLUMINATE-A
2021, Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1

---

ASTRAL
2009, Revascularization versus Medical Therapy for Renal-Artery Stenosis

---

APECS
2019, Verubecestat for Prodromal Alzheimer’s Disease

---

RE-SPECT CVT
2019, Dabigatran Etexilate vs Dose-Adjusted Warfarin in Patients With Cerebral Venous Thrombosis

---

STRIVE
2017, Erenumab in Episodic Migraine

---

CLARITY
2010, Oral Cladribine for Relapsing Multiple Sclerosis

---

MGTX
2016, Thymectomy in Myasthenia Gravis

---

LEAP
2019, Early vs Delayed Levodopa in Parkinson’s Disease

---

RAMPART
2012, Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus

---

ACTIVE A
2009, Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation

---

LACTIN-V
2020, Lactin-V to Prevent Recurrence of Bacterial Vaginosis

---

TRAAP2
2021, Tranexamic acid for the prevention of blood loss after cesarean delivery

---

Lifestyle Modification in Infertility
2016, Lifestyle Program in Obese Infertile Women

---

35/39
2016, Labor Induction in Women 35 Years of Age or Older

---

Aspirin for Preeclampsia
2017, Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

---

ONTT
1992, Corticosteroids in the Treatment of Acute Optic Neuritis

---

Action Seniors
2021, Home-based exercise program as a fall prevention strategy among high-risk older adults after a fall

---

EPCAT I
2013, Aspirin Versus LMWH for Extended VTE Prophylaxis After Total Hip Arthroplasty

---

Antimicrobials in Otitis Media
2011, Antimicrobial Treatment for Acute Otitis Media

---

COAST
2021, Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia

---

COMBINE
2006, Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence

---

SOARS-B
2021, Intranasal oxytocin in children and adolescents with autism spectrum disorder

---

BALANCE
2010, Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder

---

ANTLER
2021, Maintenance or discontinuation of antidepressants in primary care

---

CBT, Imipramine in Panic Disorder
2000, Cognitive-Behavioral Therapy, Imipramine, or Their Combination for Panic Disorder

---

ACURASYS 
2010, Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome

---

AMAZES
2017, Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma

---

ASCENT-COPD
2019, Effect of Aclidinium Bromide on Major CV Events and Exacerbations in Patients With COPD

---

CHECK-UP
2018, Checklist for Endotracheal Intubation of Critically Ill Adults

---

3SITES
2015, Intravascular Complications of Central Venous Catheterization by Insertion Site

---

INBUILD
2019, Nintedanib in Progressive Fibrosing Interstitial Lung Diseases

---

HIGH-WEAN
2019, Postextubation High-Flow Nasal Oxygen + Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone

---

SAVE
2016, CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea

---