bleeding
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PEGASUS-TIMI 54 Trial: Long-Term Ticagrelor After Prior Myocardial Infarction
The PEGASUS-TIMI 54 trial was a major randomized clinical trial that evaluated whether long-term treatment with ticagrelor, added to aspirin, reduces cardiovascular events in patients with a prior myocardial infarction. The key finding was straightforward: ticagrelor reduced cardiovascular death, myocardial infarction, or stroke, but increased major bleeding. Background Patients who have had a myocardial infarction…