Orthopedics
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SOLARIO Trial: Short-Course Antibiotics Are Noninferior After Surgery for Orthopedic Infection
The SOLARIO trial, published in the New England Journal of Medicine in 2026, challenges the traditional practice of prolonged systemic antibiotic therapy after surgery for orthopedic infection. In this randomized noninferiority trial, investigators examined whether patients who received locally implanted antibiotics during surgery could safely receive a much shorter course of postoperative systemic antibiotics. The…