Gastroenterology
-
H. pylori Infection: A Clinical Cheat Sheet for Diagnosis, Treatment, and Test-of-Cure
Helicobacter pylori is one of the most important infections in gastroenterology. It commonly colonizes the gastric mucosa and may remain silent for years, but when clinically relevant, it is strongly linked with chronic active gastritis, peptic ulcer disease, upper GI bleeding, gastric adenocarcinoma, and gastric MALT lymphoma. Chronic infection can cause long-standing gastric inflammation and…
-
WATERFALL Trial: Aggressive vs Moderate Fluid Resuscitation in Acute Pancreatitis
Clinical question: In adults with acute pancreatitis, does early aggressive fluid resuscitation improve outcomes compared with a more moderate fluid strategy? Acute pancreatitis is one of those conditions where “give fluids early” has been drilled into clinical practice for years. The logic makes sense: patients may be volume depleted, pancreatic microcirculation may be impaired, and…