Gastroenterology
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WATERFALL Trial: Aggressive vs Moderate Fluid Resuscitation in Acute Pancreatitis
Clinical question: In adults with acute pancreatitis, does early aggressive fluid resuscitation improve outcomes compared with a more moderate fluid strategy? Acute pancreatitis is one of those conditions where “give fluids early” has been drilled into clinical practice for years. The logic makes sense: patients may be volume depleted, pancreatic microcirculation may be impaired, and…