Category: Endocrinology

Algorithm: Daignostic Workup of Primary Aldosteronism

Primary Aldosteronism Diagnosis Algorithm Primary aldosteronism is characterized by elevated plasma aldosterone levels that leads potassium loss, hypertension secondary to sodium reabsorption and volume expansion and at times metabolic alkalosis. In order to discuss the diagnostic approach for primary aldosteronism in terms of both blood tests and imaging tests, I have designed this algorithm after..

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ACCORD Trial (2008): Effects of Intensive Glucose Lowering in Type 2 Diabetes

ACCORD Trial Summary: Gerstein et al randomized 10,251 patients with type 2 diabetes mellitus, hemoglobin A1c ≥7.5% with CAD or ≥2 cardiovascular risk factors (dyslipidemia, HTN, current smoking, obesity) to either standard glycemic control HbA1c 7-7.9% (n=5,123) or intensive glycemic control HbA1c <6% (n=5,128). The primary objective was to assess if intensive glycemic control targeting..

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