CABG
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NOBLE Trial: PCI vs CABG for Unprotected Left Main Coronary Artery Disease
Introduction The NOBLE trial was an important randomized clinical trial comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) in patients with unprotected left main coronary artery disease. Left main coronary artery disease is clinically important because the left main artery supplies a large portion of the myocardium. Revascularization is usually required, but…
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EXCEL Trial: PCI or CABG for Left Main Coronary Artery Disease
Introduction The EXCEL trial was a major randomized clinical trial comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) in patients with left main coronary artery disease. Left main disease is one of the most important forms of coronary artery disease because the left main artery supplies a large portion of the heart…
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SYNTAX Trial: PCI vs CABG for Severe Coronary Artery Disease
The SYNTAX trial was a landmark randomized controlled trial comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) in patients with complex coronary artery disease, specifically those with three-vessel disease and/or left main coronary artery disease. This trial helped shape modern decision-making for patients with severe coronary artery disease and remains one of…