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SAGA/SITE Trial: Can Statins Be Safely Stopped After Age 75 for Primary Prevention?
Whether statins should be continued indefinitely in older adults without established cardiovascular disease remains one of the more uncertain areas of preventive cardiology. Randomized statin trials have demonstrated clear cardiovascular benefit in many populations, but adults older than 75 years—particularly those receiving statins exclusively for primary prevention—have historically been underrepresented. The SAGA/SITE trial, published in…