Infectious Disease
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H. pylori Infection: A Clinical Cheat Sheet for Diagnosis, Treatment, and Test-of-Cure
Helicobacter pylori is one of the most important infections in gastroenterology. It commonly colonizes the gastric mucosa and may remain silent for years, but when clinically relevant, it is strongly linked with chronic active gastritis, peptic ulcer disease, upper GI bleeding, gastric adenocarcinoma, and gastric MALT lymphoma. Chronic infection can cause long-standing gastric inflammation and…
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SCORPIO-PEP Trial: Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts
The SCORPIO-PEP trial evaluated ensitrelvir as postexposure prophylaxis for household contacts of Covid-19 patients and showed a significant reduction in symptomatic Covid-19 by day 10. Introduction The SCORPIO-PEP trial evaluated whether ensitrelvir, an oral antiviral agent, could prevent Covid-19 in people recently exposed to SARS-CoV-2 within their household. Household exposure remains one of the highest-risk…