The USPSTF and ACC/AHA guidelines for statin use in adults aged 40-75 years are consistent over level of recommendation. Adults who have no history of cardiovascular disease but have 1 or more risk factors for developing CVD along with >10% ASCVD risk are recommended to be started on low- to moderate dose statin. (USPSTF = B). The ACC/AHA however recommends moderate to high dose statin for ASCVD risk of >7.5% for primary prevention (ACC/AHA Level I). The above visual abstract summarizes both the societies’ recommendations in to one easy to use graphic.