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LESS: Epidural Glucocorticoid Injections for Spinal Stenosis

 

2014, epidural glucocorticoid + lidocaine vs lidocaine only injections for spinal stenosis, NEJM

PRECISION Trial: Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis

This visual abstract represents the important findings of the PRECISION trial. The trial compares the COX-2 selective NSAID celecoxib with traditionally used NSAIDs such as naproxen and ibuprofen. It establishes non inferiority in terms of cardiovascular events and superiority in terms of GI and renal safety. As of March 2017, no guidelines have been published that reflect the results of this trial.

Source: NEJM

SPACE Trial: Effect of Opioid vs Nonopioid Medications on Pain-Related Function

Source: JAMA

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