Tag: hepatology

Bezafibrate in Primary Biliary Cholangitis

A Placebo-controlled Trial of Bezafibrate in Primary Biliary Cholangitis Trial Summarized by: Hajra Munawar, MBBS Hasan Shafiq, MD Contribution to literature This trial revealed that the use of the Bezafibrate (PPAR-a agonist )add-on therapy with ursodeoxycholic acid (UDCA) in patients with primary biliary cholangitis, normalizes the serum levels of alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase,..

Read more

STOPAH Trial: Prednisolone or Pentoxifylline for Alcoholic Hepatitis

The use of steroids vs Pentoxifylline in severe alcoholic hepatitis has long been debated. The STOPAH trial published in NEJM in 2015 was a strong 2×2 factorial design, randomized trial that established that neither pentoxifylline nor prednisolone provided significant survival benefit in patients with severe alcoholic hepatitis. Take a look at my visual abstract for..

Read more