Tag: heart failure

COMMANDER HF Trial (2018): Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease

COMMANDER HF Trial Summary: Zannand F et al. randomized 5,022 patients with coronary artery disease and heart failure to undergo treatment with either rivaroxaban or a placebo. The primary objective of the study was to assess if rivaroxaban could reduce thrombin production and improve outcomes in patients with CAD and HF. The results showed that rivaroxaban..

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TRED-HF Trial (2019): Withdrawal of treatment for HF in patients with recovered DCM

TRED-HF Trial Summary: Halliday et al. randomized 51 patients with dilated cardiomyopathy (LVEF<40%) who recovered with the improvement of symptoms to either continual treatment with HF medications or withdrawal of HF therapy. The objective was to assess the safety of withdrawing treatment in patients with dilated cardiomyopathy whose symptoms and cardiac function have recovered. The results showed significant replase..

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MOMENTUM 3 Trial (2018): Magnetically Levitated Cardiac Pump in Heart Failure

MOMENTUM 3 Trial Summary: Mehra et al. randomized 366 patients with advanced HF (NYHA class III-IV, LVEF ≤ 25%), inotrope dependant, cardiac index < 2.2 without inotropes to either HeartMate III (centrifugal-flow LVAD) or HeartMate II (axial-flow LVAD). Their objective was to assess if is a magnetically levitated centrifugal-flow LVAD is superior to an axial-flow..

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BLOCK HF: Biventricular versus Right Ventricular Pacing in Heart Failure Patients with AV Block

  2013, Biventricular versus Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block, NEJM BLOCK HF Trial Summary The Biventricular versus Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block (BLOCK HF) trial is a prospective, multicentric, double-blinded, industry (Medtronic) sponsored, randomized controlled trial conducted to evaluate role of biventricular (BiV) pacing in..

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