atrial fibrillation

AF-CHF Trial Summary: Rhythm vs Rate Control for AFib and HF

AF-CHF: Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure Multicenter, prospective, randomized, controlled trial Objective: To assess if rhythm-control reduce CV mortality in patients with AF and HFrEF as compared to rate control. Patients with AF and … Read More

ACTIVE W Trial Summary: Clopidogrel + ASA vs. OAC for Atrial Fibrillation

2006 ACTIVE W TRIAL Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation Randomized, open treatment, controlled trial M Objective: Among patients with nonvalvular AF, how does combination aspirin/clopidogrel compare to warfarin in reducing the incidence of stroke, systemic embolism, … Read More

ACTIVE A Trial Summary: Clopidogrel + Aspirin in Atrial Fibrillation

2009 ACTIVE A TRIAL Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation Multicenter, double-blind, parallel-group trial M Objective: To assess if the addition of clopidogrel to aspirin reduces the risk of vascular events compared to aspirin alone … Read More

LOOP Trial: ILR for AFib to Prevent Stroke

2021 LOOP TRIAL Implantable loop recorder detection of atrial fibrillation to prevent stroke open-label, randomized controlled trial Objective: To assess the efficacy and safety of continuous monitoring for atrial fibrillation (AF) with an implantable loop recorder (ILR) versus usual care … Read More

AATAC Trial Summary: Ablation vs. amiodarone for Persistent Atrial Fibrillation

2016 AATAC TRIAL Ablation vs. amiodarone for treatment of persistent atrial fibrillation in CHF Multicenter, parallel-group, open-label, randomized Objective: To assess if AF ablation is superior to y amiodarone in patients with symptomatic (NYHA II-III) heart failure with reduced ejection … Read More

PALACS Trial Summary: Posterior Left Pericardiotomy for Post-op AFib

2021 PALACS TRIAL M Posterior left pericardiotomy for the prevention of postoperative atrial fibrillation after cardiac surgery Randomized, parallel, stratified, single-centre study Objective: To evaluate posterior left pericardiotomy compared with no intervention among patients undergoing open heart surgery 420 patients … Read More