Topic
Year
Recent
ACTION
2021, Therapeutic vs. prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer
ANTHARTIC
2019, Prevention of early Ventilator-Associated Pneumonia after cardiac arrest
ARREST 2020
2020, Advanced reperfusion strategies for patients with out-ofhospital cardiac arrest and refractory ventricular fibrillation
ATACAS
2017, Tranexamic Acid in patients undergoing coronary artery surgery
ATESS
2020, Combination therapy of vitamin C and thiamine for septic shock
AVATAR
2021, Aortic Valve Replacement versus Conservative treatment in Asymptomatic Severe Aortic Stenosis
Beta-Blocker Therapy in TBI
2020, Beta-Blocker Therapy in Severe Traumatic Brain Injury
CERTA
2020, Continuous vs routine electroencephalogram in critically ill adults with altered consciousness and no recent seizure
CHECK-UP: POSITION
2017, Ramped position vs Sniffing position during endotracheal intubation of critically ill adults
COBI
2021, Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury
DIRECT-MT
2020, Endovascular thrombectomy with or without intravenous alteplase in acute stroke
DREAMS
2017, Dexamethasone vs standard treatment for postoperative nausea and vomiting (PONV) in gastrointestinal surgery
EAT-ICU
2017, Early goal-directed nutrition versus standard of care in adult intensive care patients
EMPULSE
2021, Empagliflozin in patients hospitalized for Acute Heart Failure
EPICC
2017, Intensive versus standard physical rehabilitation therapy in the critically ill
ESETT
2019, Randomized trial of three anticonvulsant medications for Status Epilepticus
FIESTY
2021, Fibrinogen early in severe trauma study
ICE-CUB 2
2017, Effect of systematic intensive care unit triage on long-term mortality among critically ill elderly patients in France
INPRESS
2017, Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery
KEYNOTE-826
2021, Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer
LOCO2
2020, Liberal or conservative oxygen therapy for Acute Respiratory Distress Syndrome
MIDAS
2020, Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit
MK-6482-004
2021, Belzutifan for Renal Cell Carcinoma in von Hippel–Lindau Disease
MR CLEAN–NO IV
2021, Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke
MoDUS
2017, Early treatment with Simvastatin in critically ill Delirium patients
NONSEDA
2020, Nonsedation or light sedation in critically ill, mechanically ventilated patients
PALACS
2021, Posterior left pericardiotomy for the prevention of postoperative atrial fibrillation after cardiac surgery
PARADISE-MI
2021, Angiotensin Receptor–Neprilysin Inhibition in Acute Myocardial Infarction
PEPTIC
2020, Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive mechanical ventilation
PGT-A for Aneuploidy
2021, Live birth with or without preimplantation genetic testing for aneuploidy
RECONNECT
2017, Reconnection to mechanical ventilation (MV) for 1h after a successful spontaneous breathing trial (SBT) reduces reintubation in critically ill patients.
REDECAP
2020, High-flow oxygen with capping or suctioning for tracheostomy decannulation
SHENFU
2017, Efficacy and safety of combination therapy of Shenfu injection and post resuscitation bundle in patients with return of spontaneous circulation(ROSC) after in-hospital cardiac arrest
SSSP-2
2017, Effect of an Early Resuscitation Protocol on In-hospital mortality among adults with Sepsis and Hypotension
TRANSFUSE
2017, Age of red cells(RBC) for transfusion and outcomes in critically ill adults
TTM 48
2017, Targeted Temperature Management for 48 vs 24 hours and neurologic outcome after out-of-Hospital Cardiac Arrest (OOHCA)
VAM-IHCA
2021, Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest
VITAMINS
2021, Effect of Vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock
