PROVE IT Trial (2004): Intensive vs Moderate Lipid Lowering with Statins after ACS
PROVE IT Trial Summary
In 2004, Dr. Cannon et al. randomly assigned over 4,162 patients with acute coronary syndrome within past 10 days to either high dose atorvastatin 80 mg or moderate dose 40 mg pravastatin. Their goal was to assess
The authors concluded that among patients with
The current ESC, as well as ACC/AHA
guidelinesrecommend starting all patients with ACS on high dose statin therapy.
Grade IA. Source
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