Prednisolone or Pentoxifylline for Alcoholic Hepatitis – STOPAH Trial
The use of steroids vs Pentoxifylline in severe alcoholic hepatitis has long been debated. The STOPAH trial published in NEJM in 2015 was a strong 2x2 factorial design, randomized trial that established that neither pentoxifylline nor prednisolone provided significant survival benefit in patients with severe alcoholic hepatitis. Take a look at my visual abstract for the trial. You can use it free for educational purposes.
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