The DAWN trial was a major success when it comes to mechanical thromebectomy eligibility time.Both the DAWN and DEFUSE 3 trial led to modification of AHA/ACC 2018 guidelines for stroke which recommended that in selected acute stroke patients within 6-24 hours of last known normal who have large vessel occlusion in the anterior circulation and meet other DAWN eligibility criteria, mechanical thrombectomy with a stent retriever is reasonable.

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