Rheumatology
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Amyloidosis: Recognition, Diagnosis, and Treatment Clinical Cheat Sheet
Amyloidosis comprises a heterogeneous group of disorders characterized by extracellular deposition of misfolded proteins as amyloid fibrils. The clinical phenotype depends on the precursor protein, the organs involved, and the extent of tissue deposition. The most important systemic forms encountered in clinical practice are immunoglobulin light-chain amyloidosis, or AL amyloidosis; transthyretin amyloidosis, or ATTR amyloidosis;…