Category: Infectious Disease - page 2

MERINO Trial: Piperacillin-Tazobactam vs Meropenem in ESBL infections

MERINO Trial: 2018, Pip-Tazo vs Meropenem in patients with E-coli or Klebsiella infections,  JAMA Earlier cohort studies yielded conflicting results when it comes to treating ceftriaxone-resistant E-coli and Klebsiella infections. Some studies reported noninferiority of piperacillin-tazobactam when compared to meropenem while others reported almost doubling of mortality. In the MERINO trial, the patients were randomized to assess for..

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Tenofovir versus Placebo to Prevent Perinatal Transmission of Hepatitis B

Summarized by / Author: Rooma Nankani MD (1), Rohini Manaktala MD (1) Summary Reviewer: Paul Robert Anthony Jr. MD (2) Contribution To Literature: This trial showed that the maternal use of tenofovir in hepatitis B positive mothers did not result in significantly lower rate of perinatal hepatitis B transmission. However, it is known that the rate of mother to..

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