Category: General Medicine

PANSAID Trial (2019): Paracetamol and Ibuprofen on Morphine Consumption in the Total Hip Arthroplasty

PANSAID Trial Summary: Hojgaard et al. randomized 556 patients who were scheduled to undergo total hip arthroplasty to pain control with a combination of paracetamol + ibuprofen or any one of them with placebo. The primary objective was to assess if post-op morphine requirement decreases with the use of adjunctive pain medications. The results showed significant decrease in morphine requirement when paracetamol..

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SPRINT MIND Trial (2019): Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia

SPRINT-MIND Trial Summary: Authors of this trial randomized 9,361 adults aged 50 years or older with hypertension but without diabetes or history of stroke to either intensive control (SBP < 120 mmHg) or standard control (SBP < 140 mmHg). The objective was to assess if intensive blood pressure control reduces the occurrence of dementia as..

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