Category: Emergency Medicine

PARAMEDIC2 Trial: Epinephrine in Out-of-Hospital Cardiac Arrest

The PARAMEDIC2 trial that was recently published in NEJM studied the use of epinephrine in the out-of-hospital cardiac arrest and compared the final outcome of survival with placebo. Patients who had a cardiac arrest out of hospital were treated with the standard resuscitation protocol. The patient population which was given epinephrine compared to placed were..

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PAMPer Trial: Prehospital Plasma in Trauma Patients

PAMPer trial is a multicenter randomized trial that evaluated the use of thawed plasma in addition to standard resuscitation measures in patients at risk of subsequent hemorrhagic shock. The results showed a significant 30-day mortality benefit in patients who received plasma transfusion in addition to standard resuscitation while en route to a trauma center. Source: NEJM

Basic Modes of Mechanical Ventilation Infographic

Mechanical ventilation is a complex topic to understand. With this infographic, I have tried to explain 4 most commonly used ventilator modes in intensive care units. The two broad categories are the volume limited and pressure limited ventilation while each of them have further sub-branches. In future posts, I’m going to create a basic flowchart..

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Algorithm for Management of Adult Patients with DKA

Diabetic ketoacidosis requires emergent intervention and treatment. The treatment of DKA requires careful monitoring of both acidosis as well as blood glucose levels. In order to streamline the treatment process, I have designed the following algorithm keeping in mind the complexity of the disease. This management algorithm is based on the American Diabetes association updated..

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ProACT Trial: Procalcitonin-Guided Antibiotics for Lower Respiratory Tract Infection

Procalcitonin has proven to be a great marker for guiding antibiotics treatment in patients with concern for lower respiratory tract infections. However, it’s not yet established how much does clinicians adhere to using the antibiotic therapy based on procalcitonin results. The ProACT trial recently got published in NEJM. It showed that despite it’s usefulness, clinicians..

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