Title: Colonoscopy versus fecal immunochemical testing
Design: Multicenter randomized, controlled noninferiority trial
Objective: Is fecal immunochemical testing (FIT) every 2 years noninferior to colonoscopy in terms of reduction of colorectal cancer mortality?
Year of publication: 2012
Inclusion Criteria: FIT, every 2 years (n=26,703) vs Colonoscopy, one time (n=26,599)
Comparison groups: AF ablation (n=203) vs amiodarone (n=203)
Conclusion: Subjects in the FIT group were more likely to participate in screening than were those in the colonoscopy group. the numbers of subjects in whom colorectal cancer was detected were similar in the two study groups Source: N Engl J Med 2012; 366:697-706 | Quintero E, et al. | visualmed.org