LVH Criteria on ECG 🧠 Remember: ECG has low sensitivity but high specificity for LVH. ✅ Sokolow-Lyon Criteria ✅ Cornell Criteria ✅ Romhilt-Estes Point Score System ⚡ LVH-Associated ST-T Changes (Strain Pattern)
Latest Clinical Trials

Hyponatremia Management Algorithm
1. Starting Point Hyponatremia 2. Step 1: Rule out non-hypotonic causes 3. Step 2: Assess severity Decision: Acute or severe symptoms? 4. Step 3: Urine Osmolality Decision: Urine osmolality 5. Step 4: Urine Sodium Decision: Urine sodium 6. Step 5: … Read More

FARES-II Trial: PCC vs FFP in Cardiac Surgery
FARES-II Trial: PCC Outperforms Frozen Plasma in Managing Coagulopathic Bleeding During Cardiac Surgery In the FARES-II trial, researchers investigated whether Prothrombin Complex Concentrate (PCC) could offer superior outcomes compared to frozen plasma for patients undergoing cardiac surgery who develop coagulopathic … Read More

Right Heart Catheterization: A Quick Interpretation Guide
Right Heart Catheterization (RHC) is a critical tool for diagnosing and managing various cardiovascular and pulmonary conditions. This invasive hemodynamic assessment provides real-time insight into the function and pressures of the right heart, pulmonary arteries, and left heart indirectly via … Read More

Altshock-2 Trial: IABP in Cardiogenic Shock
Altshock-2 Trial: Evaluating Early IABP Support in Cardiogenic Shock The Altshock-2 trial is a multicenter, prospective study designed to evaluate the efficacy of early intra-aortic balloon pump (IABP) support in patients with heart failure-related cardiogenic shock (HF-CS). This trial aimed … Read More
ASSET-IT Trial: Early Tirofiban Infusion in Stroke
The 2025 ASSET-IT trial investigated whether early intravenous infusion of tirofiban, an antiplatelet agent, following intravenous thrombolysis could improve outcomes in patients with acute noncardioembolic ischemic stroke who are not eligible for thrombectomy. This phase 3, double-blind, randomized, placebo-controlled study … Read More

E3 Trial: Do e-Cigarettes Help Smokers Quit?
Published in JACC Advances, June 2025 The E3 Trial evaluated whether short-term use of nicotine or non-nicotine e-cigarettes, combined with counseling, improves smoking abstinence at 1 year. This multicenter, randomized controlled trial adds critical insight into smoking cessation strategies. 🧑⚕️ … Read More

Advance-HTN Trial: Lorundrostat in Uncontrolled Hypertension
Hypertension remains a major global health issue, particularly for patients whose blood pressure remains uncontrolled despite multiple medications. The Advance-HTN trial, presented at ACC.25 in Chicago in 2025, provides compelling evidence for the use of lorundrostat, a novel aldosterone synthase … Read More

DapaTAVI Trial: Dapagliflozin in TAVR
The year 2025 brought several influential cardiovascular studies to light, and among the most promising was the DapaTAVI trial. This randomized, open-label trial explored the impact of dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, in a population often seen as high-risk … Read More