Year: 2024 Title: FULL REVASC Subtitle: FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction Type of Trial: A registry-based, randomized, parallel, blinded trial Objective: To evaluate the benefit of fractional flow reserve (FFR)–guided complete revascularization compared with usual … Read More
MI
Beta Blockers After MI and Preserved EF
Year: 2024 Title: REDUCE-AMI Subtitle: Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction Type of Trial: A randomized, parallel-group, open-label trial Objective: To determine whether long-term treatment with oral beta-blockade in patients with myocardial infarction and preserved left ventricular systolic … Read More
DAPA-MI Trial: Dapagliflozin in MI
DAPA-MI Trial: Dapagliflozin in MI? The DAPA-MI Trial, as reported in the New England Journal of Medicine in 2023, was a randomized, double-blind clinical trial designed to assess the safety and efficacy of dapagliflozin, a medication typically used to treat … Read More
FIRE Trial: Complete PCI in MI in Older Patients
The FIRE trial, published in the New England Journal of Medicine in 2023, was a multicenter, randomized controlled trial that aimed to evaluate the benefits of complete revascularization versus culprit-lesion-only percutaneous coronary intervention (PCI) in older patients (≥75 years of … Read More
TRAVERSE Trial: CV Safety of Testosterone-Replacement Therapy
TRAVERSE Trial Summary The abstract highlights the findings of the TRAVERSE trial, which aimed to assess the cardiovascular safety of testosterone-replacement therapy in middle-aged and older men with hypogonadism. The trial sought to determine whether testosterone replacement therapy in this … Read More
RITA 3 Trial: Interventional vs. Conservative Strategy in UA/NSTEMI
RITA 3 Trial Summary Background: Methods: Findings: Interpretation: Key Takeaways: Source
SECURE Trial Summary: Polypill Strategy in Secondary Cardiovascular Prevention
2022 SECURE TRIAL Polypill Strategy in Secondary Cardiovascular Prevention Phase 3, randomized, controlled clinical trial Objective: To evaluate the effect of polypill that includes key medications (aspirin, ramipril, and atorvastatin) on cardiovascular events in post-Ml patients. 2499 Inclusion criteria: Patients … Read More
TRANSFER AMI Trial Summary: Early Angioplasty after Fibrinolysis for Acute MI
2009 TRANSFER-AMI trial: Routine Early Angioplasty after Fibrinolysis for Acute Myocardial Infarction Multicenter, randomized, non-blinded, parallel Assignment Objective: To assess outcomes in patients with AMI treated with thrombolysis transferring to a center providing PCI for standard treatment (rescue PCI or … Read More