2022 PERSPECTIVE TRIAL M Efficacy and safety of sacubitril/valsartan compared to valsartan on cognitive function in patients with chronic heart failure and preserved ejection fraction parallel, randomized controlled trial Objective: To evaluate the effectiveness of sacubitril/valsartan compared with valsartan alone … Read More
heart failure
A-HEFT Trial Summary: Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure
2004 -0.1 3.1 A-HEFT TRIAL Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure Inclusion criteria: patients self-identified as 1,050 black (of African descent) with NYHA class III-IV patients HF ≥3 months on standard therapy, including ACEI/ARBs, ẞ-blockers, … Read More
AATAC Trial Summary: Ablation vs. amiodarone for Persistent Atrial Fibrillation
2016 AATAC TRIAL Ablation vs. amiodarone for treatment of persistent atrial fibrillation in CHF Multicenter, parallel-group, open-label, randomized Objective: To assess if AF ablation is superior to y amiodarone in patients with symptomatic (NYHA II-III) heart failure with reduced ejection … Read More
TAVR with Self-Expanding Prosthesis Trial Summary
2014 COREVALVE HIGH-RISK TRIAL Transcatheter aortic-valve replacement (TAVR) with a self-expanding prosthesis Multicenter, randomized, non inferiority trial “‘Objective: To compare TAVR using a self-expanding a transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis & an … Read More
ADVOR Trial Summary: Acetazolamide in Acute Decompensated Heart Failure with Volume Overload
2022 ADVOR STUDY Acetazolamide in acute decompensated heart failure with volume overload multicenter, parallel-group, double-blind, randomized, placebo-controlled trial a d Objective: To compare the incidence of successful decongestion with addition of acetazolamide vs placebo to loop diuretic therapy in patients … Read More
METEORIC-HF Trial Summary: Omecamtiv Mecarbil Effect of Exerciser in HFrEF
2022 METEORIC-HF Effect of Omecamtiv mecarbil on exercise capacity in chronic heart failure with reduced ejection fraction Phase 3, double-blind, placebo-controlled randomized trial a Objective: To determine whether omecamtiv mecarbil, a novel direct myosin activator improves peak exercise capacity in … Read More
SODIUM-HF Trial Summary: Reduction of dietary sodium in Heart Failure
2022 SODIUM-HF TRIAL Reduction of dietary sodium to less than 100 mmol in heart failure International, open-label, randomised, controlled trial Objective: To evaluate if a low-sodium diet (<1500 mg daily) compared to usual care in ambulatory patients with heart failure … Read More
EMPULSE Trial Summary: Empagliflozin in Acute Heart Failure
2021 EMPULSE TRIAL Empagliflozin in patients hospitalized for Acute Heart Failure Randomized, parallel trial Objective: To evaluate empagliflozin compared with placebo among patients with acute decompensated heart failure. 530 patients Inclusion criteria: Patients hospitalized for acute HF regardless of ejection … Read More
PARADISE MI Trial Summary: Sacubitril-valsartan vs ramipril in acute MI
2021 PARADISE-MI M Angiotensin Receptor-Neprilysin Inhibition in Acute Myocardial Infarction international, multicenter, randomized, double-blind, active-comparator trial S S 1. Objective: To compare the effects of sacubitril-valsartan and angiotensin converting-enzyme inhibitor, ramipril in patients with acute myocardial infarction 5661 Inclusion criteria: … Read More
PARADISE MI Trial: Is Sacubitril/valsartan (Entresto) useful in patients with acute MI?
The PARADISE MI trial is the first of the 10 new trials visual abstracts that we have added to the app. You can download the JPEG of the visual abstract from below. You can use it any way you like … Read More