Visual Summaries of Randomized Controlled Trials
The RECORD trial was a prospective, randomized, open-label trial that assessed if addition of rosiglitazone to either metformin or sulfonylurea increase the rate of adverse CV outcomes as compared to the combination of metformin and…
The AF-CHF trial is a multicenter, prospective, randomized, controlled trial that assessed if rhythm-control reduces CV mortality in patients with AF and HFrEF as compared to rate control. 1,376 patients with nonvalvular atrial fibrillation and…
COMMANDER HF Trial Summary: Zannand F et al. randomized 5,022 patients with coronary artery disease and heart failure to undergo treatment with either rivaroxaban or a placebo. The primary objective of the study was to assess…
TRED-HF Trial Summary: Halliday et al. randomized 51 patients with dilated cardiomyopathy (LVEF<40%) who recovered with the improvement of symptoms to either continual treatment with HF medications or withdrawal of HF therapy. The objective was to assess the safety…
MOMENTUM 3 Trial Summary: Mehra et al. randomized 366 patients with advanced HF (NYHA class III-IV, LVEF ≤ 25%), inotrope dependant, cardiac index < 2.2 without inotropes to either HeartMate III (centrifugal-flow LVAD) or HeartMate…
AF-CHF Trial Summary: Roy D et al. randomized 1,376 patients with nonvalvular atrial fibrillation and HFrEF (LVEF ≤35% and NYHA II-IV symptoms) were randomized to rhythm control (pharmacologic or electrical approach) or rate control…
2007, Levosimendan in acute decompensated heart failure, JAMA
2013, Biventricular versus Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block, NEJM BLOCK HF Trial Summary The Biventricular versus Right Ventricular Pacing in Heart Failure Patients with Atrioventricular Block (BLOCK HF) trial…