Visual Summaries of Randomized Controlled Trials
The objective of FIRE AND ICE trial is to compare balloon cryoablation with traditional radiofrequency ablation (RFA) in terms of long-term atrial fibrillation-free survival in patients with symptomatic paroxysmal atrial fibrillation (PAF). Patients with symptomatic…
Cryptogenic stroke has long been associated with PFO and underlying undetected atrial fibrillation. The EMBRACE trial was an important step forward. It hypothesized that many of the patients with cryptogenic stroke had underlying AF that…
The AF-CHF trial is a multicenter, prospective, randomized, controlled trial that assessed if rhythm-control reduces CV mortality in patients with AF and HFrEF as compared to rate control. 1,376 patients with nonvalvular atrial fibrillation and…
BRIDGE Trial Summary: Douketis JD et al. randomized 1,884 patients on warfarin (INR 2-3 for ≥3m) with AF or A-flutter and CHADS2 Score ≥1 to LMWH: dalteparin (100 IU/kg BID) or placebo. The objective was…
AF-CHF Trial Summary: Roy D et al. randomized 1,376 patients with nonvalvular atrial fibrillation and HFrEF (LVEF ≤35% and NYHA II-IV symptoms) were randomized to rhythm control (pharmacologic or electrical approach) or rate control…
2018, Catheter Ablation for AF with Heart Failure, NEJM
2011, Apixaban vs. warfarin in atrial fibrillation, NEJM
2011, Rivaroxaban vs. warfarin in atrial fibrillation, NEJM