EMPEROR Reduced Trial: Empagliflozin in HFrEF
The SGLT-2 inhibitors were initially developed for diabetes but eventually noted to have significant effects on …
Category Archives: Cardiovascular Disease
REALITY Trial: Transfusion in Patients With Myocardial Infarction and Anemia
Multiple small trials in the past have shown benefits of liberal transfusion strategy in patients having …
EAST AFNET 4 Trial: Early Rhythm control in Afib
In patients with nonvalvular afib, rate control was considered to be no different than rhythm control …
EXPLORER-HCM Trial: Mavacamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Mavacamten is a novel cardiac-specific myosin ATPase inhibitor. It specifically reduces excessive cross-bridging with actin, which …
PADIT Trial: Prevention of Arrhythmia Device Infection Trial
PADIT Trial Summary The PADIT Trial (Prevention of Arrhythmia Device Infection Trial) was a cluster randomized …
WRAP-IT Trial: Antibacterial Envelope to Prevent Device Infections
WRAP-IT trial summary WRAP-IT trial is a multicenter, randomized, controlled, prospective, single-blind trial that was published …
WOSCOPS Trial: Prevention of CAD with Pravastatin
WOSCOPS Trial Summary WOSCOPS trial was a double-blind, parallel-group, randomized, placebo-controlled trial that was designed to …
WOEST Trial: clopidogrel ± aspirin in patients taking PO anticoagulants and undergoing PCI
WOEST Trial Summary: The WOEST trial was a multicenter, open-label, randomized, controlled clinical trial to assess …
WARFASA Trial: Aspirin for preventing the recurrence of VTE
WARFASA Trial Summary The WARFASA trial was a multicenter, double-blinded, randomized, placebo-controlled trial to assess whether …
VOYAGER PAD Trial: Rivaroxaban in PAD after Revascularization
VOYAGER PAD trial aimed to determine if adding rivaroxaban to aspirin would affect outcomes in patients …