Cardiovascular Nephrology

ACT Trial: Acetylcysteine in patients undergoing Angiography

ACT trial on angiography visual abstract

ACT trial was the initial large sized randomized controlled trial that was initiated to test the role of acetylcysteine in protecting kidneys from contrast. More than 2000 patients were enrolled in this placebo-controlled trial. The results failed to establish any renal protective role of acetylcysteine in patients undergoing coronary or peripheral angiography.