Hypertension remains a major global health issue, particularly for patients whose blood pressure remains uncontrolled despite multiple medications. The Advance-HTN trial, presented at ACC.25 in Chicago in 2025, provides compelling evidence for the use of lorundrostat, a novel aldosterone synthase … Read More
Clinical Trials at your Fingertips!
Revolutionizing Medical Reference with Quick, Accessible Summaries of Landmark Clinical Trials - Right at Your Fingertips.
Latest Clinical Trials
DapaTAVI Trial: Dapagliflozin in TAVR
The year 2025 brought several influential cardiovascular studies to light, and among the most promising was the DapaTAVI trial. This randomized, open-label trial explored the impact of dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, in a population often seen as high-risk … Read More
WARRIOR Trial: Women’s Ischemia Trial, Treating Non-Obstructive Coronary Artery Disease
In the ever-evolving landscape of cardiovascular research, the WARRIOR trial—short for Women’s Ischemia Trial to Reduce Events in Non-Obstructive CAD—has emerged as a pivotal investigation into how best to treat women with ischemia and no obstructive coronary artery disease (INOCA). … Read More
API-CAT Trial: Evaluating Low-Dose Apixaban for Cancer-Associated Thrombosis
API-CAT Trial: Evaluating Low-Dose Apixaban for Cancer-Associated Thrombosis Introduction The API-CAT trial is a groundbreaking study designed to evaluate whether a reduced dose of apixaban (2.5 mg twice daily) is as effective as the standard full-dose regimen (5 mg twice … Read More
BASIL-3 Trial: Evaluating Endovascular Strategies in Severe Leg Ischaemia
Staying up to date with landmark clinical trials is essential for evidence-based patient care, especially in fields like vascular surgery and interventional cardiology. The recently published BASIL-3 trial sheds light on the best endovascular approach for patients with chronic limb-threatening … Read More
Aortic Stenosis Severity Algorithm
Aortic Stenosis Severity Algorithm (ACC/AHA 2020 Guidelines) Step 1: Assess Aortic Valve Morphology and Function Step 2: Quantify AS Severity (Echocardiographic Parameters) Severity AVA (cm²) Mean Gradient (mmHg) Peak Velocity (m/s) Dimensionless Index (DI) Mild >1.5 <20 <3.0 >0.5 Moderate … Read More
IVUS-ACS Trial: Intravascular Ultrasound vs. Angiography for PCI in Acute Coronary Syndromes
IVUS-ACS Trial Summary Introduction In the management of acute coronary syndrome (ACS), optimal guidance for percutaneous coronary intervention (PCI) remains a critical factor in improving patient outcomes. The IVUS-ACS trial, a large, multicenter, randomized study, investigates whether intravascular ultrasound (IVUS)-guided … Read More
ADAPT-Sepsis Trial: PCT vs. CRP-Guided Antibiotic Duration
Understanding the ADAPT-Sepsis Trial: PCT vs. CRP-Guided Antibiotic Duration Sepsis remains a critical challenge in intensive care units (ICUs), often requiring prolonged antibiotic use. The ADAPT-Sepsis trial, published in JAMA (2024), aimed to determine whether procalcitonin (PCT)-guided or C-reactive protein … Read More
VT vs. SVT with Abberation Infographic
VT vs SVT with Aberration: A Quick Interpretation Guide Introduction Distinguishing ventricular tachycardia (VT) vs supraventricular tachycardia (SVT) with aberrancy is a critical skill in electrophysiology and emergency medicine. Misdiagnosis can lead to inappropriate treatment and adverse outcomes. This blog … Read More